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PDF fileSee also D Fonseca & P Carvalho (August 2019) Introduction The function of cells depends on the integrity of their proteome Proteomes of eukaryotic cells are estimated to consist of tens of millions of proteins (eg 50 × 106 proteins in S cerevisiae) (Ghaemmaghami et al 2003 Milo 2013) Among those cellular quality control networks detect and selectively degrade proteins.

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